Description
People with diabetes have a deficiency or absence of a hormone made by the pancreas called insulin. Insulin is the main hormone responsible for controlling sugar (glucose) in the blood.
People with type 1 diabetes need to have insulin injections to control the amount of glucose in their bloodstream. Insulin injections replace natural insulin and allow people with diabetes to reach normal levels of glucose in the blood.
Insulin works in the same way as natural insulin, by binding to insulin receptors on cells in the body. Insulin causes cells in the liver, muscle and fatty tissue to increase their absorption of glucose form the bloodstream. It also decreases the production of glucose by the liver, and has various other effects which reduce the amount of glucose in the blood.
Humulin M3 contains a mixture of two types of insulin, soluble insulin and isophane insulin. Together, this combination of insulin is called biphasic isophane insulin. Humulin M3 contains 30% soluble insulin and 70% isophane insulin.
Soluble insulin is known as short-acting insulin. It begins to work quickly, within 30 to 60 minutes, and its effects last for about eight hours. Isophane insulin is known as an intermediate-acting insulin. It takes longer to work, but its effects last longer. The pre-mixed combination provides a rapid initial blood sugar lowering effect, followed by a prolonged effect that controls blood sugar levels throughout the day. It is usually injected under the skin about 30 minutes before a meal.
It is important to monitor your blood sugar regularly and adjust your insulin dose as needed. Your doctor or diabetic team will explain how to do this. Keeping your blood sugar as close to normal as possible, and not too high or too low, greatly reduces the risk of developing late-stage diabetic complications.
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